Reversible abnormal chromatin clumping in granulocytes from six transplant patients treated with mycophenolate mofetil: a rare adverse effect mimicking abnormal chromatin clumping syndrome
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چکیده
منابع مشابه
The syndrome of abnormal chromatin clumping in leukocytes.
A65-year-old female was admitted to our Institute for anemia-related symptoms. The hematological findings were as follows: Hb 65 g/L, platelet count 45310/L; WBC 18310/L with neutrophils 74%, lymphocytes 8%; monocytes 2%, promyelocytes 2%, myelocytes 12%, metamyelocytes 2%. When observed under the microscope, neutrophils were characterized by loss of segmentation (pelgeroid features) and abnorm...
متن کاملChromatin clumping in mature leukocytes: a hitherto unrecognized abnormality.
1rOfll tIl(’ Departnic’nt of ‘%Ie(licine, Marquette School of ‘iiedicine, Blood Research I.4ahoratorl,, ?tIilW(tUkCC Count , General HoSpital, ltfiltvaukee, %Vis. Aided by Research Grant CA-05524-()8, Training Grant AM-05162-10, Clinical Research Center Grant 5-M01-RR00058-09, from the National In.ctitutes of Health, United States Public Health Service, Bethesda, Md.; the American Cancer Societ...
متن کاملCorrelation of abnormal histology with endoscopic findings among mycophenolate mofetil treated patients
AIM To describe all abnormal histological findings and their associated endoscopic presentation in patients using mycophenolate mofetil (MMF). METHODS A retrospective review of all individuals prescribed MMF within 6 mo of a colonoscopy or flexible sigmoidoscopy between 07/2009 and 09/2015 was performed within Northwell Health system. Records were analyzed for age, gender, procedure indicatio...
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Mutations in the maternal-effect gene abnormal chromatin (abc) in Drosophila melanogaster result in a variety of defects involving nuclear replication/division. Three recessive alleles of this gene, which maps near 51F on chromosome 2, all result in female sterility. They cause slower embryonic development that is usually abnormal from the earliest nuclear divisions and arrested by the sixth on...
متن کاملInfundibuloneurohypophysitis Associated With Sjögren Syndrome Successfully Treated With Mycophenolate Mofetil
Hypophysitis is an inflammatory disorder of the pituitary gland and corticosteroids are usually recommended as the first-line treatment. Hypophysitis related to primary Sjögren syndrome (pSS) is uncommon. We describe the unusual case of a patient with infundibuloneurohypophysitis associated with pSS successfully treated with mycophenolate mofetil (MMF).We describe a case of a 60-year-old man wi...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 2002
ISSN: 0007-1048
DOI: 10.1046/j.1365-2141.2002.3317_2.x